The HOXA7 Polyclonal Antibody (CAB12891) is a vital tool for researchers studying the HOXA7 protein, which plays a crucial role in regulating gene expression and cell differentiation. This antibody, produced in rabbits, exhibits high specificity towards human samples and is validated for use in Western blotting applications.HOXA7 is a member of the HOX family of transcription factors, known for their involvement in embryonic development and tissue patterning. As a key regulator of gene expression, HOXA7 has been implicated in various cellular processes, including cell growth, apoptosis, and differentiation.
Understanding the function of HOXA7 is essential for unraveling its role in development, as well as its potential implications in diseases like cancer and developmental disorders.By utilizing the HOXA7 Polyclonal Antibody (CAB12891), researchers can accurately detect and analyze HOXA7 expression in different cell types, providing valuable insights into its biological functions. This antibody serves as a valuable tool in molecular and cellular biology studies, offering new possibilities for research in developmental biology, oncology, and beyond.
Product Name:
HOXA7 Rabbit Polyclonal Antibody
SKU:
CAB12891
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HOXA7 (NP_008827.2).
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.
Purification Method:
Affinity purification
Gene ID:
3204
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of THP-1, using HOXA7 antibody (CAB12891) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
