The HOXA2 Polyclonal Antibody (CAB9658) is a valuable tool for researchers studying the HOXA2 protein, a critical regulator of gene expression involved in embryonic development and cell differentiation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in various applications, including Western blotting and immunohistochemistry.HOXA2 is a transcription factor that plays a crucial role in controlling the expression of genes involved in patterning and morphogenesis during development. Dysregulation of HOXA2 has been associated with developmental disorders and cancer, highlighting its importance in cell growth and differentiation processes.
By detecting and analyzing HOXA2 expression levels in different cell types, researchers can gain insights into its function and potential therapeutic targets for developmental disorders and cancer treatment.Overall, the HOXA2 Polyclonal Antibody is a reliable tool for researchers investigating the role of HOXA2 in development, differentiation, and disease, providing crucial information for advancing our understanding of gene regulation and potential therapeutic interventions.
Product Name:
HOXA2 Rabbit Polyclonal Antibody
SKU:
CAB9658
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 207-376 of human HOXA2 (NP_006726.1).
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.
Purification Method:
Affinity purification
Gene ID:
3199
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HOXA2 antibody (CAB9658) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
