The HOXA13 Rabbit Monoclonal Antibody (CAB9564) is a valuable tool for research involving the HOXA13 protein, a transcription factor that plays a crucial role in development and differentiation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.HOXA13 is known for its role in regulating gene expression and cell fate determination, particularly in the development of various tissues and organs. Studies have linked dysregulation of HOXA13 to developmental disorders, cancer, and other diseases, highlighting the importance of understanding its function and activity.
By targeting the HOXA13 protein, researchers can investigate its impact on cellular processes and disease pathways, providing valuable insights into developmental biology, oncology, and regenerative medicine. The HOXA13 Rabbit Monoclonal Antibody offers researchers a reliable tool for exploring the functions and mechanisms of this critical transcription factor in both normal and diseased states.
Product Name:
HOXA13 Rabbit Monoclonal Antibody
SKU:
CAB9564
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human HOXA13 (P31271).
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Purification Method:
Affinity purification
Gene ID:
3209
Clone Number:
ARC1636
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HOXA13 Rabbit mAb (CAB9564) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
