The HOXA11 Polyclonal Antibody (CAB2976) is a vital tool for researchers studying the HOXA11 protein, a key transcription factor involved in embryonic development and cellular differentiation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the HOXA11 protein, allowing for accurate detection and analysis in a variety of cell types.HOXA11 plays a crucial role in the regulation of gene expression during development, making it a focus of interest in studies related to embryogenesis, tissue regeneration, and cancer biology.
By targeting HOXA11, researchers can gain valuable insights into the mechanisms underlying these processes and potentially uncover new therapeutic targets for a range of diseases.Overall, the HOXA11 Polyclonal Antibody is an essential tool for investigating the functions and regulatory networks involving HOXA11, paving the way for advancements in developmental biology, regenerative medicine, and cancer research.
Product Name:
HOXA11 Rabbit Polyclonal Antibody
SKU:
CAB2976
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HOXA11 (NP_005514.1).
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.
Purification Method:
Affinity purification
Gene ID:
3207
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HOXA11 antibody (CAB2976) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
