The HOXA10 Polyclonal Antibody (CAB8550) is a valuable tool for researchers studying the HOXA10 protein, a key player in developmental processes and gene regulation. This antibody, produced in rabbits, boasts high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to HOXA10, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in developmental biology and cancer research.HOXA10 is a critical transcription factor that controls the expression of genes involved in cell growth, differentiation, and organ development.
Its dysregulation has been implicated in a variety of diseases, including cancers and developmental disorders. Understanding the function of HOXA10 is essential for unraveling its role in these conditions and identifying potential therapeutic targets.By utilizing the HOXA10 Polyclonal Antibody (CAB8550), researchers can gain valuable insights into the molecular mechanisms governing development and disease, ultimately paving the way for the development of novel treatments and interventions.
Product Name:
HOXA10 Rabbit Polyclonal Antibody
SKU:
CAB8550
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 236-336 of human HOXA10 (NP_061824.3).
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene.
Purification Method:
Affinity purification
Gene ID:
3206
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HOXA10 antibody (CAB8550) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
