The HOOK3 Polyclonal Antibody (CAB15536) is an essential tool for researchers studying the HOOK3 protein, a key component of the endocytic pathway and microtubule organization. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot analysis.HOOK3 is involved in various cellular processes, including intracellular transport, ciliary biogenesis, and cell division. Its dysfunction has been linked to developmental disorders and neurodegenerative diseases, making it a crucial target for investigation in the fields of cell biology and neuroscience.
By utilizing the HOOK3 Polyclonal Antibody, researchers can accurately detect and analyze HOOK3 protein expression in different cell types, shedding light on its role in cellular functions and disease mechanisms. This antibody is a valuable tool for advancing our understanding of HOOK3 biology and exploring potential therapeutic strategies targeting this protein.
Product Name:
HOOK3 Rabbit Polyclonal Antibody
SKU:
CAB15536
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 489-718 of human HOOK3 (NP_115786.1).
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.
Purification Method:
Affinity purification
Gene ID:
84376
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HOOK3 Rabbit pAb (CAB15536) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
