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HOMER1 Monoclonal Antibody [PAT1F3AT] (CPAB0540)

SKU:
CPAB0540
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1F3AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

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HOMER1 Monoclonal Antibody [PAT1F3AT] (CPAB0540)

The Homer1 Polyclonal Antibody (CPAB0540) is a valuable tool for research involving the Homer1 protein, which is known for its role in regulating synaptic plasticity and neuronal function. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blotting and immunofluorescence applications.Homer1 is a scaffolding protein that plays a crucial role in organizing and anchoring signaling molecules at the post-synaptic density of excitatory synapses. Dysregulation of Homer1 expression has been implicated in various neurological disorders, including Alzheimer's disease, schizophrenia, and depression.

By targeting Homer1 with this antibody, researchers can investigate its function and potential involvement in these conditions.Furthermore, the Homer1 Polyclonal Antibody enables the detection and visualization of Homer1 protein localization in different cell types and tissues, making it a versatile tool for neuroscience research. By understanding the role of Homer1 in synaptic plasticity and neuronal function, researchers may uncover new therapeutic targets for treating neurological disorders.

Product Name:HOMER1 Antibody
Product Sku:CPAB0540
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HOMER1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HOMER1 amino acids 1-354 purified from Ecoli.
Clone:PAT1F3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:HOMER1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:HOMER1 takes part in determining the apoptotic susceptibility to TRAIL. HOMER1 is a member of the Homer family of proteins that regulate signal transduction through, and the trafficking of, glutamate receptors, plus maintain and regulate extracellular glutamate levels in corticolimbic brain regions. The HOMER1 is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs).
Synonyms:HOMER, SYN47, Ves-1, HOMER1A, HOMER1B, HOMER1C, HOMER1, Homer protein homolog 1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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