The HNRPLL Polyclonal Antibody (CAB10360) is a valuable tool for researchers studying HNRPLL, a key protein involved in RNA processing and gene regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting HNRPLL in human samples, making it suitable for use in Western blot applications.HNRPLL, also known as heterogeneous nuclear ribonucleoprotein L-like, plays a crucial role in post-transcriptional regulation of gene expression by influencing mRNA splicing and stability.
Dysregulation of HNRPLL has been linked to various diseases, including cancer and neurological disorders, making it an attractive target for further investigation.By using the HNRPLL Polyclonal Antibody, researchers can gain insights into the function and expression patterns of HNRPLL in different cell types and tissues. This antibody is a valuable tool for advancing our understanding of RNA processing mechanisms and their implications in disease development and progression.
Product Name:
HNRPLL Rabbit Polyclonal Antibody
SKU:
CAB10360
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human HNRPLL (NP_612403.2).
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).
Purification Method:
Affinity purification
Gene ID:
92906
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HNRNPLL antibody (CAB10360) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
