The HNRNPUL1 Polyclonal Antibody (PACO09768) is a valuable tool for researchers studying HNRNPUL1, a key protein involved in RNA processing and gene expression regulation. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By targeting the HNRNPUL1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a versatile tool for investigations in molecular biology and disease mechanisms.HNRNPUL1, also known as heterogeneous nuclear ribonucleoprotein U like 1, plays a crucial role in mRNA splicing and stability, making it an essential player in gene expression regulation.
Its involvement in post-transcriptional processes and RNA binding interactions makes it a promising target for research on diseases such as cancer, neurodegenerative disorders, and developmental abnormalities. By uncovering the functions of HNRNPUL1, researchers can gain insights into its potential as a therapeutic target for various pathological conditions.
E1B-AP5: a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. Binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Four alternatively spliced isoforms have been described. Protein type: RNA splicing; RNA-bindingChromosomal Location of Human Ortholog: 19q13.2Cellular Component: nucleoplasm; nucleus; ribonucleoprotein complexMolecular Function: protein binding; enzyme binding; RNA bindingBiological Process: nuclear mRNA splicing, via spliceosome; RNA processing; transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA splicing; response to virus; gene expression
UniProt Protein Details:
NCBI Summary:
This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Heterogeneous nuclear ribonucleoprotein U-like protein 1
NCBI Synonym Full Names:
heterogeneous nuclear ribonucleoprotein U-like 1
NCBI Official Symbol:
HNRNPUL1Â Â
NCBI Official Synonym Symbols:
E1BAP5; E1B-AP5; HNRPUL1Â Â
NCBI Protein Information:
heterogeneous nuclear ribonucleoprotein U-like protein 1; E1B 55kDa associated protein 5; E1B-55kDa-associated protein 5; E1B-55 kDa-associated protein 5; adenovirus early region 1B-associated protein 5
UniProt Protein Name:
Heterogeneous nuclear ribonucleoprotein U-like protein 1
UniProt Synonym Protein Names:
Adenovirus early region 1B-associated protein 5; E1B-55 kDa-associated protein 5; E1B-AP5