The HNRNPU Polyclonal Antibody (CAB3917) is a valuable tool for researchers studying HNRNPU, a multifunctional RNA-binding protein involved in various cellular processes, including RNA splicing, stability, and transport. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.HNRNPU, also known as heterogeneous nuclear ribonucleoprotein U, is a key player in gene expression regulation and has been implicated in a wide range of biological functions, such as DNA damage response, chromatin organization, and development.
Its dysregulation has been associated with various human diseases, including cancer, neurodegenerative disorders, and viral infections.By targeting the HNRNPU protein, researchers can gain insights into its role in cellular processes and pathophysiological conditions, paving the way for the development of potential therapeutic strategies targeting HNRNPU-related pathways. The HNRNPU Polyclonal Antibody (CAB3917) is a valuable resource for unraveling the complex functions of HNRNPU and its implications in health and disease.
Product Name:
hnRNP U Rabbit Polyclonal Antibody
SKU:
CAB3917
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 608-825 of human hnRNP U (NP_114032.2).
This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14.
Purification Method:
Affinity purification
Gene ID:
3192
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using hnRNP U Rabbit pAb (CAB3917) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
