HNRNPM Rabbit Polyclonal Antibody (CAB6937)
- SKU:
- CAB6937
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | HNRNPM Rabbit Polyclonal Antibody |
SKU: | CAB6937 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 491-730 of human HNRNPM (NP_005959.2). |
Sequence: | GFGL ERMA APID RVGQ TIER MGSG VERM GPAI ERMG LSME RMVP AGMG AGLE RMGP VMDR MATG LERM GANN LERM GLER MGAN SLER MGLE RMGA NSLE RMGP AMGP ALGA GIER MGLA MGGG GGAS FDRA IEME RGNF GGSF AGSF GGAG GHAP GVAR KACQ IFVR NLPF DFTW KMLK DKFN ECGH VLYA DIKM ENGK SKGC GVVK FESP EVAE RACR MMNG MKLS GREI DVRI DRNA |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CEAR; HNRPM; HTGR1; NAGR1; HNRPM4; HNRNPM4; hnRNP M; HNRNPM |
Positive Sample: | BT-474,HL-60,Mouse thymus,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleolus. |
Calculated MW: | 78kDa |
Observed MW: | 78kDa |
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4670 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |