HNRNPL Rabbit Polyclonal Antibody (CAB8430)
- SKU:
- CAB8430
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | HNRNPL Rabbit Polyclonal Antibody |
SKU: | CAB8430 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 282-589 of human HNRNPL (NP_001524.2). |
Sequence: | TWDY TNPN LSGQ GDPG SNPN KRQR QPPL LGDH PAEY GGPH GGYH SHYH DEGY GPPP PHYE GRRM GPPV GGHR RGPS RYGP QYGH PPPP PPPP EYGP HADS PVLM VYGL DQSK MNCD RVFN VFCL YGNV EKVK FMKS KPGA AMVE MADG YAVD RAIT HLNN NFMF GQKL NVCV SKQP AIMP GQSY GLED GSCS YKDF SESR NNRF STPE QAAK NRIQ HPSN VLHF FNAP LEVT EENF FEIC DELG VKRP SSVK VFSG KSER SSSG LLEW ESKS DALE TLGF LNHY QMKN PNGP YPYT LKLC FSTA QHAS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | HNRPL; hnRNP-L; P/OKcl.14; HNRNPL |
Positive Sample: | U-87MG,HeLa,HepG2,A-549,HT-29,Mouse ovary,Rat lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleoplasm. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3191 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |