The HNRNPK Polyclonal Antibody (CAB1701) is a valuable tool for researchers studying the heterogeneous nuclear ribonucleoprotein K (HNRNPK) protein. This antibody, produced in rabbit, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the HNRNPK protein, researchers can easily detect and analyze this key protein in a variety of cell types.HNRNPK is involved in various cellular processes, including RNA metabolism, transcriptional regulation, and DNA repair. Its role in gene expression and protein synthesis makes it an important target for studies in molecular biology and cancer research.
By understanding the function of HNRNPK, researchers can gain insights into disease mechanisms and potentially identify new therapeutic targets.Overall, the HNRNPK Polyclonal Antibody (CAB1701) is a valuable tool for studying the HNRNPK protein and its role in cellular processes. Its high reactivity and specificity make it an ideal choice for researchers looking to delve deeper into the molecular mechanisms of gene regulation and protein expression.
Product Name:
hnRNP K Rabbit Polyclonal Antibody
SKU:
CAB1701
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human hnRNP K (NP_112552.1).
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.
Purification Method:
Affinity purification
Gene ID:
3190
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using hnRNP K Rabbit pAb (CAB1701) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
