HNRNPF Rabbit Polyclonal Antibody (CAB5505)
- SKU:
- CAB5505
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | HNRNPF Rabbit Polyclonal Antibody |
SKU: | CAB5505 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human HNRNPF (NP_001091678.1). |
Sequence: | MMLG PEGG EGFV VKLR GLPW SCSV EDVQ NFLS DCTI HDGA AGVH FIYT REGR QSGE AFVE LGSE DDVK MALK KDRE SMGH RYIE VFKS HRTE MDWV LKHS GPNS ADSA NDGF VRLR GLPF GCTK EEIV QFFS GLEI VPNG ITLP VDPE GKIT GEAF VQFA SQEL AEKA LGKH KERI GHRY IEVF KSSQ EEVR SYSD PPLK FMSV QRPG PYDR PGTA RRYI GIVK QAGL ERMR PGAY STGY GGYE EYSG LSDG YGFT TDLF GRDL SYCL SGMY DHRY GDSE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 |
Synonyms: | HNRPF; mcs94-1; OK/SW-cl.23; PF |
Positive Sample: | 22Rv1,Lovo,MCF7,BT-474,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleoplasm. |
Calculated MW: | 46kDa |
Observed MW: | 47kDa |
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 3185 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |