The HNRNPF Polyclonal Antibody (CAB5505) is a valuable tool for researchers studying HNRNPF, a key protein involved in RNA processing and gene expression regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the HNRNPF protein, researchers can accurately analyze its expression levels in various cell types, making it an excellent choice for studies in molecular biology and genomics.HNRNPF is a multi-functional protein with diverse roles in RNA splicing, transport, and translation.
Its involvement in various cellular processes makes it a potential target for investigating diseases related to RNA dysregulation, such as cancer and neurological disorders. By exploring the functions of HNRNPF, researchers can gain insights into how disruptions in RNA metabolism contribute to disease development and progression.Overall, the HNRNPF Polyclonal Antibody (CAB5505) offers researchers a reliable tool for studying the functions of HNRNPF in cellular processes and disease pathways, providing valuable information for the development of targeted therapies and diagnostic tools.
Product Name:
HNRNPF Rabbit Polyclonal Antibody
SKU:
CAB5505
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human HNRNPF (NP_001091678.1).
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
3185
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HNRNPF antibody (CAB5505) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
