HNRNPD Rabbit Polyclonal Antibody (CAB15679)
- SKU:
- CAB15679
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | HNRNPD Rabbit Polyclonal Antibody |
SKU: | CAB15679 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human HNRNPD (NP_002129.2). |
Sequence: | MSEE QFGG DGAA AAAT AAVG GSAG EQEG AMVA ATQG AAAA AGSG AGTG GGTA SGGT EGGS AESE GAKI DASK NEED EGHS NSSP RHSE AATA QREE WKMF IGGL SWDT TKKD LKDY FSKF GEVV DCTL KLDP ITGR SRGF GFVL FKES ESVD KVMD QKEH KLNG KVID PKRA KAMK TKEP VKKI FVGG LSPD TPEE KIRE YFGG FGEV ESIE LPMD NKTN KRRG FCFI TFKE EEPV KKIM EKKY HNVG LSKC EIKV AMSK EQYQ QQQQ WGSR GGFA GRAR GRGG DQQS GYGK VSRR GGHQ NSYK PY |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | P37; AUF1; AUF1A; HNRPD; hnRNPD0; HNRNPD |
Positive Sample: | HeLa,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 38kDa |
Observed MW: | 37-45kDa |
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 3184 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |