hnRNP A1 Rabbit Polyclonal Antibody (CAB7491)
- SKU:
- CAB7491
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | hnRNP A1 Rabbit Polyclonal Antibody |
SKU: | CAB7491 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-372 of human hnRNP A1 (NP_112420.1). |
Sequence: | MSKS ESPK EPEQ LRKL FIGG LSFE TTDE SLRS HFEQ WGTL TDCV VMRD PNTK RSRG FGFV TYAT VEEV DAAM NARP HKVD GRVV EPKR AVSR EDSQ RPGA HLTV KKIF VGGI KEDT EEHH LRDY FEQY GKIE VIEI MTDR GSGK KRGF AFVT FDDH DSVD KIVI QKYH TVNG HNCE VRKA LSKQ EMAS ASSS QRGR SGSG NFGG GRGG GFGG NDNF GRGG NFSG RGGF GGSR GGGG YGGS GDGY NGFG NDGG YGGG GPGY SGGS RGYG SGGQ GYGN QGSG YGGS GSYD SYNN GGGG GFGG GSGS NFGG GGSY NDFG NYNN QSSN FGPM KGGN FGGR SSGP YGGG GQYF AKPR NQGG YGGS SSSS SYGS GRRF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | UP 1; ALS19; ALS20; HNRPA1; IBMPFD3; HNRPA1L3; hnRNP A1; hnRNP-A1 |
Positive Sample: | A-549,Jurkat,HepG2,HL-60,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 39kDa |
Observed MW: | 39kDa |
This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.
Purification Method: | Affinity purification |
Gene ID: | 3178 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |