The HNRNP K Rabbit Monoclonal Antibody is a highly specific and sensitive tool for research involving the heterogeneous nuclear ribonucleoprotein K (HNRNP K) protein. This antibody, generated in rabbits, is optimized for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.HNRNP K is a multifunctional protein involved in multiple cellular processes, including transcriptional regulation, RNA splicing, and mRNA translation. It plays a crucial role in gene expression and is linked to numerous diseases, such as cancer, neurodegenerative disorders, and viral infections.
By targeting HNRNP K with this monoclonal antibody, researchers can investigate its function and potential therapeutic applications in these pathological conditions.With its high specificity and sensitivity, the HNRNP K Rabbit Monoclonal Antibody offers reliable results in detecting and analyzing HNRNP K expression in various cell types and tissues. Its versatility and accuracy make it an essential tool for studies in molecular biology, cell biology, and disease mechanisms related to HNRNP K activity.
Product Name:
hnRNP K Rabbit Monoclonal Antibody
SKU:
CAB0772
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human hnRNP K (P61978).
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.
Purification Method:
Affinity purification
Gene ID:
3190
Clone Number:
ARC0512
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using hnRNP K antibody (CAB0772) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
