HNF4A Rabbit Polyclonal Antibody (CAB2085)
- SKU:
- CAB2085
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HNF4A Rabbit Polyclonal Antibody |
SKU: | CAB2085 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 226-325 of human HNF4A (NP_849180.1). |
Sequence: | EHLL LGAT KRSM VFKD VLLL GNDY IVPR HCPE LAEM SRVS IRIL DELV LPFQ ELQI DDNE YAYL KAII FFDP DAKG LSDP GKIK RLRS QVQV SLED YIND |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; TCF-14; HNF4alpha; HNF4A |
Positive Sample: | SW480 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 53kDa |
Observed MW: | 52kDa |
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 3172 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |