HNF1B Rabbit Polyclonal Antibody (CAB3093)
- SKU:
- CAB3093
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | HNF1B Rabbit Polyclonal Antibody |
SKU: | CAB3093 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of HNF1B (NP_000449.1). |
Sequence: | MVSK LTSL QQEL LSAL LSSG VTKE VLVQ ALEE LLPS PNFG VKLE TLPL SPGS GAEP DTKP VFHT LTNG HAKG RLSG DEGS EDGD DYDT PPIL KELQ ALNT EEAA EQRA EVDR MLSE DPWR AAKM IKGY MQQH NIPQ REVV DVTG LNQS HLSQ HLNK GTPM KTQK RAAL YTWY VRKQ REIL RQFN QTVQ SS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | T2D; FJHN; HNF2; LFB3; RCAD; TCF2; HPC11; LF-B3; MODY5; TCF-2; VHNF1; ADTKD3; HNF-1B; HNF1beta; HNF-1-beta; HNF1B |
Positive Sample: | HepG2,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 61kDa |
Observed MW: | 61kDa |
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6928 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |