The HNF1B Polyclonal Antibody (CAB3093) is a valuable tool for researchers studying the hepatocyte nuclear factor 1-beta (HNF1B) protein, which plays a key role in regulating gene expression in the kidney, pancreas, and other tissues. This antibody is produced in rabbits and demonstrates high reactivity with human samples, making it an ideal choice for Western blot applications.HNF1B is known to be involved in various developmental processes and is also implicated in diseases such as diabetes and cancer.
By targeting the HNF1B protein, researchers can gain insights into its function and potentially uncover new therapeutic strategies for these conditions.This antibody enables the detection and analysis of HNF1B in different cell types, providing researchers with a valuable tool for investigating the role of this protein in health and disease. Its specificity and reliability make it a valuable asset in studies related to developmental biology, metabolism, and cancer research.
Product Name:
HNF1B Rabbit Polyclonal Antibody
SKU:
CAB3093
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of HNF1B (NP_000449.1).
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6928
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HNF1B Rabbit pAb (CAB3093) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
