HNF1A Rabbit Polyclonal Antibody (CAB3092)
- SKU:
- CAB3092
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | HNF1A Rabbit Polyclonal Antibody |
SKU: | CAB3092 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human HNF1α (NP_000536.6). |
Sequence: | LGEP GPYL LAGE GPLD KGES CGGG RGEL AELP NGLG ETRG SEDE TDDD GEDF TPPI LKEL ENLS PEEA AHQK AVVE TLLQ EDPW RVAK MVKS YLQQ HNIP Q |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | HNF1; LFB1; TCF1; HNF4A; MODY3; TCF-1; HNF-1A; IDDM20; HNF1alpha; HNF-1-alpha; HNF1α |
Positive Sample: | 293T,LO2 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 67kDa |
Observed MW: | 81kDa |
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 6927 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |