The HMMR Polyclonal Antibody (CAB12445) is a valuable tool for researchers studying Hyaluronan Mediated Motility Receptor (HMMR), a cell surface protein involved in cell migration and proliferation. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the HMMR protein, this antibody allows for the detection and analysis of HMMR in various cell types, making it an essential component of studies in cancer biology and cell motility.HMMR, also known as RHAMM (Receptor for Hyaluronic Acid-Mediated Motility), is implicated in tumor progression, metastasis, and invasion, making it a promising target for cancer research.
By understanding the role of HMMR in these processes, researchers can develop strategies for targeting HMMR in cancer therapy. Additionally, HMMR has been linked to other conditions such as inflammation and wound healing, highlighting its significance in various biological contexts.Overall, the HMMR Polyclonal Antibody (CAB12445) offers researchers a reliable tool for investigating the functions of HMMR and its potential implications in cancer and other disease states. Its specificity and sensitivity make it an ideal choice for studies aiming to elucidate the role of HMMR in cellular processes and disease mechanisms.
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
3161
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] CD168/RHAMM Rabbit pAb (CAB12445) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
