HMGN5 Antibody (PACO16795)
- SKU:
- PACO16795
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
HMGN5 Antibody (PACO16795)
The HMGN5 Polyclonal Antibody (PAC016795) offered by AssayGenie is a valuable tool for researchers studying the HMGN5 protein in various cellular and molecular processes. HMGN5, a member of the High Mobility Group N (HMGN) family, is involved in chromatin remodeling and gene expression regulation, making it a key player in epigenetic regulation.This antibody, raised in rabbits, exhibits high specificity and sensitivity for detecting HMGN5 in human samples, making it suitable for Western blot applications. By binding to HMGN5, researchers can accurately detect and analyze its expression in different cell types, providing valuable insights into its functional role in biological processes.HMGN5 has been implicated in diverse biological processes, including cell cycle regulation, DNA repair, and transcriptional activation.
Its dysregulation has been associated with various diseases, such as cancer and neurological disorders, highlighting its importance as a potential therapeutic target.By utilizing the HMGN5 Polyclonal Antibody in their research, scientists can gain a better understanding of the molecular mechanisms underlying HMGN5's functions and its implications in disease development. This antibody is a valuable tool for studies in the fields of molecular biology, cancer research, and epigenetics, offering a comprehensive approach to unraveling the complexities of HMGN5 biology.
| Antibody Name: | HMGN5 Antibody (PACO16795) |
| Antibody SKU: | PACO16795 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human HMGN5 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Raji cells, 293T cells, Hela cells, 231 cells, Primary antibody: PACO16795(HMGN5 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. |
| Background: | This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. |
| Synonyms: | high mobility group nucleosome binding domain 5 |
| UniProt Protein Function: | NSBP1: Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. Belongs to the HMGN family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: Xq13.3 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus Molecular Function:chromatin binding Biological Process: negative regulation of apoptosis; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009] |
| UniProt Code: | P82970 |
| NCBI GenInfo Identifier: | 23396771 |
| NCBI Gene ID: | 79366 |
| NCBI Accession: | P82970.1 |
| UniProt Secondary Accession: | P82970,Q5JSL1, |
| UniProt Related Accession: | P82970 |
| Molecular Weight: | 31,525 Da |
| NCBI Full Name: | High mobility group nucleosome-binding domain-containing protein 5 |
| NCBI Synonym Full Names: | high mobility group nucleosome binding domain 5 |
| NCBI Official Symbol: | HMGN5Â Â |
| NCBI Official Synonym Symbols: | NSBP1; NBP-45Â Â |
| NCBI Protein Information: | high mobility group nucleosome-binding domain-containing protein 5 |
| UniProt Protein Name: | High mobility group nucleosome-binding domain-containing protein 5 |
| UniProt Synonym Protein Names: | Nucleosome-binding protein 1 |
| Protein Family: | High mobility group nucleosome-binding domain-containing protein |
| UniProt Gene Name: | HMGN5Â Â |
| UniProt Entry Name: | HMGN5_HUMAN |
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