Anti-HMGN5 Antibody (PACO16794)

Antibody Name:	HMGN5 Antibody (PACO16794)
Antibody SKU:	PACO16794
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200
Species Reactivity:	Human
Immunogen:	Fusion protein of human HMGN5

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO16794(HMGN5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: 231 cells, Primary antibody: PACO16794(HMGN5 Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
	The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO16794(HMGN5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).

Background:	This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein.
Synonyms:	high mobility group nucleosome binding domain 5

UniProt Protein Function:	NSBP1: Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. Belongs to the HMGN family.
UniProt Protein Details:	Protein type:DNA-binding Chromosomal Location of Human Ortholog: Xq13.3 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus Molecular Function:chromatin binding Biological Process: negative regulation of apoptosis; positive regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter
NCBI Summary:	This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009]
UniProt Code:	P82970
NCBI GenInfo Identifier:	23396771
NCBI Gene ID:	79366
NCBI Accession:	P82970.1
UniProt Secondary Accession:	P82970,Q5JSL1,
UniProt Related Accession:	P82970
Molecular Weight:	31,525 Da
NCBI Full Name:	High mobility group nucleosome-binding domain-containing protein 5
NCBI Synonym Full Names:	high mobility group nucleosome binding domain 5
NCBI Official Symbol:	HMGN5
NCBI Official Synonym Symbols:	NSBP1; NBP-45
NCBI Protein Information:	high mobility group nucleosome-binding domain-containing protein 5
UniProt Protein Name:	High mobility group nucleosome-binding domain-containing protein 5
UniProt Synonym Protein Names:	Nucleosome-binding protein 1
Protein Family:	High mobility group nucleosome-binding domain-containing protein
UniProt Gene Name:	HMGN5
UniProt Entry Name:	HMGN5_HUMAN

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)