The HMGN1 Polyclonal Antibody (CAB14646) is a valuable tool for research involving HMGN1, a protein that plays a critical role in chromatin structure and gene expression regulation. The antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.HMGN1, a member of the high-mobility group nucleosome-binding protein family, is involved in modulating chromatin structure and gene transcription by binding to nucleosomes.
Its function in regulating gene expression makes it a key player in various cellular processes, including development, differentiation, and response to environmental stimuli.Researchers studying epigenetics, chromatin remodeling, and gene regulation will find the HMGN1 Polyclonal Antibody to be a valuable tool in their investigations. Its specificity and sensitivity make it ideal for detecting and analyzing HMGN1 protein levels in different cell types and tissues, providing insights into its role in health and disease.
Product Name:
HMGN1 Rabbit Polyclonal Antibody
SKU:
CAB14646
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human HMGN1 (NP_004956.5).
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.
Purification Method:
Affinity purification
Gene ID:
3150
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat brain using HMGN1 Rabbit pAb (CAB14646) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
