The HMGN1 Polyclonal Antibody (CAB6155) is a research tool designed for studying HMGN1, a high mobility group nucleosomal binding protein that plays a role in chromatin architecture and transcriptional regulation. This antibody, produced in rabbits, is highly specific to human HMGN1 and has been validated for use in Western blot applications.HMGN1 is known for its ability to modulate chromatin structure and gene expression, making it a key player in various cellular processes such as DNA repair, replication, and transcription. Research on HMGN1 has implications in cancer biology, epigenetics, and developmental biology, as dysregulation of HMGN1 expression has been linked to tumorigenesis and other diseases.
With its high specificity and proven performance in Western blotting, the HMGN1 Polyclonal Antibody is a valuable tool for investigators studying the function and regulation of HMGN1 in both normal and disease states. Its ability to detect HMGN1 protein in different cell types makes it suitable for a wide range of research applications in molecular biology and biomedicine.
Product Name:
HMGN1 Rabbit Polyclonal Antibody
SKU:
CAB6155
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HMGN1 (NP_004956.5).
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.
Purification Method:
Affinity purification
Gene ID:
3150
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HMGN1 antibody (CAB6155) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 30s.
