HMGCS2 Rabbit Polyclonal Antibody (CAB14244)
- SKU:
- CAB14244
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | HMGCS2 Rabbit Polyclonal Antibody |
SKU: | CAB14244 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 269-508 of human HMGCS2 (NP_005509.1). |
Sequence: | CYTS YRKK IQNQ WKQA GSDR PFTL DDLQ YMIF HTPF CKMV QKSL ARLM FNDF LSAS SDTQ TSLY KGLE AFGG LKLE DTYT NKDL DKAL LKAS QDMF DKKT KASL YLST HNGN MYTS SLYG CLAS LLSH HSAQ ELAG SRIG AFSY GSGL AASF FSFR VSQD AAPG SPLD KLVS STSD LPKR LASR KCVS PEEF TEIM NQRE QFYH KVNF SPPG DTNS LFPG TWYL ERVD EQHR RKYA RRPV |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:2000 - 1:8000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | HMGCS2 |
Positive Sample: | COLO 205,U-251 MG |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 57kDa |
Observed MW: | 50kDa |
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3158 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |