HMGCL Rabbit Polyclonal Antibody (CAB8052)
- SKU:
- CAB8052
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HMGCL Rabbit Polyclonal Antibody |
SKU: | CAB8052 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human HMGCL (NP_000182.2). |
Sequence: | MAAM RKAL PRRL VGLA SLRA VSTS SMGT LPKR VKIV EVGP RDGL QNEK NIVS TPVK IKLI DMLS EAGL SVIE TTSF VSPK WVPQ MGDH TEVL KGIQ KFPG INYP VLTP NLKG FEAA VAAG AKEV VIFG AASE LFTK KNIN CSIE ESFQ RFDA ILKA AQSA NISV RGYV SCAL GCPY EGKI SPAK VAEV TKKF YSMG CYEI SLGD TIGV GTPG IMKD MLSA VMQE VPLA ALAV HCHD TYGQ ALAN TLMA LQMG VSVV DSSV AGLG GCPY AQGA SGNL ATED LVYM LEGL GIHT GVNL QKLL EAGN FICQ ALNR KTSS KVAQ ATCK L |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HL; HMGCL |
Positive Sample: | U-251MG,SKOV3,BT-474,MCF7,Mouse liver,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix, Peroxisome. |
Calculated MW: | 34kDa |
Observed MW: | 30kDa |
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3155 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |