HMGB2 Rabbit Monoclonal Antibody (CAB9168)
- SKU:
- CAB9168
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HMGB2 Rabbit Monoclonal Antibody |
SKU: | CAB9168 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HMGB2 (P26583). |
Sequence: | MGKG DPNK PRGK MSSY AFFV QTCR EEHK KKHP DSSV NFAE FSKK CSER WKTM SAKE KSKF EDMA KSDK ARYD REMK NYVP PKGD KKGK KKDP NAPK RPPS |
Tested Applications: | WB IHC-P IF/ICC IP ChIP ELISA CUT&Tag |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of ChromatinCUT&Tag, 10⁵ cells /1 μg |
Synonyms: | HMG2; HMGB2 |
Positive Sample: | HeLa,HepG2,RAW264.7,THP-1,Mouse testis,Rat testis,Rat spleen,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Nucleus, Secreted. |
Calculated MW: | 24kDa |
Observed MW: | 24kDa |
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Purification Method: | Affinity purification |
Gene ID: | 3148 |
Clone Number: | ARC1460 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |