HMGB2 Rabbit Polyclonal Antibody (CAB17360)
- SKU:
- CAB17360
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HMGB2 Rabbit Polyclonal Antibody |
SKU: | CAB17360 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HMGB2 (NP_002120.1). |
Sequence: | SAFF LFCS EHRP KIKS EHPG LSIG DTAK KLGE MWSE QSAK DKQP YEQK AAKL KEKY EKDI AAYR AKGK SEAG KKGP GRPT GSKK KNEP EDEE EEEE EEDE D |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | HMG2; HMGB2 |
Positive Sample: | HeLa,293T,U-87MG,RAW264.7,PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Nucleus, Secreted. |
Calculated MW: | 24kDa |
Observed MW: | 30kDa |
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Purification Method: | Affinity purification |
Gene ID: | 3148 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |