The HMGA1 Polyclonal Antibody (CAB1635) is a crucial tool for researchers studying HMGA1, a protein associated with various cellular processes including transcriptional regulation, cell growth, and differentiation. This antibody, produced in rabbits, is highly specific and reactive in human samples, making it ideal for Western blot applications. By binding to HMGA1, this antibody facilitates the detection and analysis of the protein in a variety of cell types.HMGA1 is a key player in gene regulation and has been implicated in a wide range of diseases including cancer, diabetes, and obesity. Its ability to manipulate gene expression makes it a promising target for therapeutic interventions in these conditions.
Studying HMGA1 with this antibody can provide valuable insights into its role in disease progression and potentially lead to the development of novel treatments.Overall, the HMGA1 Polyclonal Antibody (CAB1635) offers researchers a valuable tool for investigating the functions and implications of HMGA1 in various physiological and pathological processes. Its high specificity and reliability make it an essential component in studies focused on understanding the complex roles of HMGA1 in health and disease.
Product Name:
HMGA1 Rabbit Polyclonal Antibody
SKU:
CAB1635
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HMGA1 (NP_665908.1).
This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.
Purification Method:
Affinity purification
Gene ID:
3159
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using HMGA1 Rabbit pAb (CAB1635) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
