The HMG20B Polyclonal Antibody is a vital tool for researchers studying the HMG20B protein, which is involved in chromatin remodeling and gene regulation. This antibody, generated in rabbits, shows high specificity and sensitivity when used with human samples in various research applications, including Western blotting.HMG20B, also known as high mobility group protein 20B, plays a crucial role in epigenetic regulation and transcriptional control by modifying chromatin structure. Dysregulation of HMG20B has been implicated in various diseases, including cancer and developmental disorders.
Therefore, understanding the function and expression of HMG20B is essential for unraveling its impact on gene expression and disease pathology.By utilizing the HMG20B Polyclonal Antibody, researchers can effectively detect and analyze HMG20B protein levels in different cell types, paving the way for advancements in cancer research, developmental biology, and epigenetics. This antibody is a valuable tool for investigating the mechanisms underlying HMG20B-mediated gene regulation and its potential as a therapeutic target in disease interventions.
Product Name:
HMG20B Polyclonal Antibody
SKU:
CAB21330
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human HMG20B (NP_006330.2).
Predicted to enable DNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of protein sumoylation; positive regulation of neuron differentiation; and skeletal muscle cell differentiation. Located in nuclear body.
Purification Method:
Affinity purification
Gene ID:
10362
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HMG20B antibody (CAB21330) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
