UniProt Protein Function: | HMBOX1: Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription regulation; DNA-bindingChromosomal Location of Human Ortholog: 8p21.1Cellular Component: cytoplasm; nuclear chromosome, telomeric region; nucleus; telomerase holoenzyme complexMolecular Function: double-stranded telomeric DNA binding; protein binding; protein complex binding; telomerase activity; telomeric DNA bindingBiological Process: negative regulation of transcription, DNA-dependent; positive regulation of telomerase activity; positive regulation of telomere maintenance via telomerase |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q6NT76 |
NCBI GenInfo Identifier: | 74758116 |
NCBI Gene ID: | 79618 |
NCBI Accession: | Q6NT76.1 |
UniProt Secondary Accession: | Q6NT76,Q3Y6P1, Q96GS5, Q9H701, A4K385, A8K3R8, B4DHY5 D3DSU0 |
UniProt Related Accession: | Q6NT76 |
Molecular Weight: | 49,867 Da |
NCBI Full Name: | Homeobox-containing protein 1 |
NCBI Synonym Full Names: | homeobox containing 1 |
NCBI Official Symbol: | HMBOX1Â Â |
NCBI Official Synonym Symbols: | HOT1; PBHNF; HNF1LAÂ Â |
NCBI Protein Information: | homeobox-containing protein 1 |
UniProt Protein Name: | Homeobox-containing protein 1 |
UniProt Synonym Protein Names: | |
Protein Family: | Homeobox-containing protein |
UniProt Gene Name: | HMBOX1Â Â |
UniProt Entry Name: | HMBX1_HUMAN |