The HLF Polyclonal Antibody (CAB3143) is a valuable tool for researchers studying the HLF protein, a transcription factor involved in regulating gene expression and cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the HLF protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.The HLF protein plays a critical role in controlling gene expression and cellular functions, with implications in various biological processes such as cell proliferation, differentiation, and apoptosis.
Understanding the function and regulation of HLF can provide valuable insights into disease mechanisms, particularly in cancer biology where dysregulation of transcription factors like HLF can contribute to tumorigenesis. Therefore, the HLF Polyclonal Antibody serves as a valuable tool for researchers seeking to elucidate the role of HLF in normal physiological processes and disease development.
Product Name:
HLF Rabbit Polyclonal Antibody
SKU:
CAB3143
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human HLF (NP_002117.1).
This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
3131
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HLF Rabbit pAb (CAB3143) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
