HLA-E Rabbit Polyclonal Antibody (CAB8429)
- SKU:
- CAB8429
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | HLA-E Rabbit Polyclonal Antibody |
SKU: | CAB8429 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HLA-E (NP_005507.3). |
Sequence: | MVDG TLLL LLSE ALAL TQTW AGSH SLKY FHTS VSRP GRGE PRFI SVGY VDDT QFVR FDND AASP RMVP RAPW MEQE GSEY WDRE TRSA RDTA QIFR VNLR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | QA1; HLA-6.2; HLA-E |
Positive Sample: | SKOV3,Jurkat,MCF7,HL-60,SW480 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 40kDa |
Observed MW: | 45kDa |
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Purification Method: | Affinity purification |
Gene ID: | 3133 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |