HLA-E Rabbit Polyclonal Antibody (CAB14206)
- SKU:
- CAB14206
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | HLA-E Rabbit Polyclonal Antibody |
SKU: | CAB14206 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-200 of human HLA-E (NP_005507.3). |
Sequence: | GSHS LKYF HTSV SRPG RGEP RFIS VGYV DDTQ FVRF DNDA ASPR MVPR APWM EQEG SEYW DRET RSAR DTAQ IFRV NLRT LRGY YNQS EAGS HTLQ WMHG CELG PDGR FLRG YEQF AYDG KDYL TLNE DLRS WTAV DTAA QISE QKSN DASE AEHQ RAYL EDTC VEWL HKYL EKGK ETL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | QA1; HLA-6.2; HLA-E |
Positive Sample: | HL-60,SKOV3,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 40kDa |
Observed MW: | 50kDa |
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Purification Method: | Affinity purification |
Gene ID: | 3133 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |