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HK2 Monoclonal Antibody [P1A7AT] (CPAB0137)

SKU:
CPAB0137
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P1A7AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

HK2 Monoclonal Antibody [P1A7AT] (CPAB0137)

The HK2 Monoclonal Antibody (CPAB0137) is a valuable tool for researchers studying the HK2 protein, a key player in the regulation of glucose metabolism. This antibody, produced using monoclonal mouse cells, is highly specific to human samples and is validated for use in immunohistochemistry applications. It binds specifically to the HK2 protein, allowing for precise detection and analysis in a variety of cell types.The HK2 protein, also known as hexokinase-2, is crucial for cancer cells as it allows for the rapid uptake and utilization of glucose, supporting their proliferation and survival.

By targeting HK2, researchers can gain insights into the metabolic pathways driving cancer growth and potentially develop new therapeutic strategies to disrupt these processes.Furthermore, the role of HK2 in glucose metabolism makes it a promising target for the development of novel cancer treatments that specifically target the metabolic vulnerabilities of tumor cells. The HK2 Monoclonal Antibody (CPAB0137) is a valuable tool for researchers interested in understanding the role of HK2 in cancer biology and exploring its potential as a therapeutic target.

Product Name:HK2 Antibody
Product Sku:CPAB0137
Size:5μg
Host Species:Mouse
Immunogen:Anti-human Hexokinase-2 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Hexokinase-2 amino acids 1-917 purified from Ecoli.
Clone:P1A7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:Hexokinase-2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase 2 is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Synonyms:Hexokinase-2, EC 2.7.1.1, HK2, Hexokinase type II, HK II, Muscle form hexokinase, HXK2, DKFZp686M1669.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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