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HIV-2 gp39 Monoclonal Antibody [NYRHIV2gp39] (CPAB0385)

SKU:
CPAB0385
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Virus
Host Species:
Mouse
Isotype:
IgG1
Clone:
NYRHIV2gp39
€660
Frequently bought together:

Description

system_update_alt Datasheet

HIV-2 gp39 Monoclonal Antibody [NYRHIV2gp39] (CPAB0385)

The HIV-2 gp39 Antibody (CPAB0385) is a valuable tool for researchers studying HIV-2 infection and progression. This polyclonal antibody, raised in rabbits, is highly specific and reactive with samples from individuals infected with HIV-2. Validated for use in various applications, including Western blot analysis, this antibody binds to the gp39 protein, allowing for the detection and analysis of HIV-2 in different cell types.HIV-2 gp39 is a crucial protein involved in the replication and pathogenesis of HIV-2, the less common and less virulent strain of the HIV virus.

Understanding the role of gp39 in HIV-2 infection can lead to insights into the development of new therapies and treatment strategies for this particular strain of the virus. This antibody is essential for researchers investigating the biology of HIV-2 and exploring potential targets for antiviral drug development. Overall, the HIV-2 gp39 Antibody (CPAB0385) is a reliable tool for researchers interested in studying HIV-2 and its unique characteristics, offering valuable insights into the biology and pathogenesis of this important virus.

Product Name:HIV-2 gp39 antibody
Product Sku:CPAB0385
Size:500μg
Host Species:mouse
Immunogen:r.gp24
Clone:NYRHIV2gp39.
Reactivity:Viral
Applications:
Purification Method:Ion exchange column.
Isotype:IgG1
Background:Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses.
Synonyms:
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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