HIV-1 p24 Monoclonal Antibody [YDHIV1gp24] (CPAB0384)
- SKU:
- CPAB0384
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Virus
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- YDHIV1gp24
Description
HIV-1 p24 Monoclonal Antibody [YDHIV1gp24] (CPAB0384)
The HIV-1 p24 Monoclonal Antibody (CPAB0384) is a valuable tool for researchers studying Human Immunodeficiency Virus Type-1 (HIV-1). This antibody, generated in mouse, is highly specific and sensitive for detecting the p24 protein of HIV-1 in human samples. Validated for use in various applications including enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry, this antibody allows for precise detection and analysis of HIV-1 p24 in biological samples.The HIV-1 p24 protein is a core protein of the virus, essential for its structure and function during viral replication.
Detection and quantification of HIV-1 p24 are crucial for monitoring viral load, disease progression, and treatment efficacy in individuals infected with HIV-1. This antibody provides researchers with a reliable tool for investigating the presence and levels of HIV-1 p24, aiding in the study of HIV pathogenesis, drug development, and vaccine research.
Product Name: | HIV-1 p24 antibody |
Product Sku: | CPAB0384 |
Size: | 500μg |
Host Species: | mouse |
Immunogen: | r.HIV-1p24 |
Clone: | YDHIV1gp24. |
Reactivity: | Viral |
Applications: |
Purification Method: | Ion exchange column. |
Isotype: | IgG1 |
Background: | Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. |
Synonyms: | |
Storage Buffer: | In lyophilized form, for long periods, store at 4C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20C. |