HIV 1 gp41 Monoclonal Antibody (CPAB0707)
- SKU:
- CPAB0707
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Virus
Description
HIV 1 gp41 Monoclonal Antibody (CPAB0707)
The HIV-1 gp41 Antibody (CPAB0707) is a highly specific antibody designed for research involving the gp41 protein of the Human Immunodeficiency Virus Type 1 (HIV-1). The antibody, produced in rabbits, shows exceptional reactivity with human HIV-1 samples and has been validated for use in various applications, including Western blot and immunohistochemistry.The gp41 protein is a crucial component of the HIV-1 envelope glycoprotein complex and plays a key role in viral entry into host cells. By targeting the gp41 protein, researchers can gain valuable insights into the mechanisms of HIV-1 infection and potential therapeutic strategies against the virus.
This antibody allows for the detection and analysis of gp41 in different cell types, making it an invaluable tool for studies in virology, immunology, and antiretroviral drug development.Understanding the structure and function of the gp41 protein is essential for advancing our knowledge of HIV-1 pathogenesis and progression. The HIV-1 gp41 Antibody (CPAB0707) provides researchers with a reliable tool for investigating the biology of the virus and developing new approaches for combating HIV/AIDS.
Product Name: | HIV 1 gp41 Antibody |
Product Sku: | CPAB0707 |
Size: | 1ml |
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Reactivity: | Viral |
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Background: | Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. |
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Storage Buffer: | Store at -20°C. |