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HIV-1 gp120 [NYRHIV1gp120] (CPAB0383)

SKU:
CPAB0383
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
€660
Frequently bought together:

Description

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HIV-1 gp120 [NYRHIV1gp120] (CPAB0383)

The HIV-1 gp120 PNdmN Antibody (CPAB0383) is an essential tool for researchers studying the HIV-1 virus and its interactions with host cells. This polyclonal antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for a variety of research applications, including Western blotting and immunofluorescence.Targeting the gp120 protein of the HIV-1 virus, this antibody enables the detection and analysis of this key viral component in various cell types. By studying the interactions between gp120 and host cells, researchers can gain valuable insights into the mechanisms of HIV infection and develop potential therapeutic interventions.

Furthermore, the HIV-1 gp120 PNdmN Antibody is crucial for understanding the immune responses elicited by the virus, paving the way for new approaches to vaccine development and antiretroviral therapy. Its versatility and specificity make it an indispensable tool for researchers in the fields of virology, immunology, and infectious diseases. Unlock the secrets of HIV-1 with the HIV-1 gp120 PNdmN Antibody (CPAB0383).

Product Name:HIV-1 gp120 (PNDmn) antibody
Product Sku:CPAB0383
Size:500μg
Host Species:mouse
Immunogen:r.gp12 (MN strain)
Clone:NYRHIV1gp120.
Reactivity:Viral
Applications:
Purification Method:Ion exchange column.
Isotype:IgG1
Background:Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses.
Synonyms:
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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