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HIV-1 gp120 Monoclonal Antibody (CPAB0714)

SKU:
CPAB0714
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Virus
Applications:
WB
ELISA
$179
Frequently bought together:

Description

system_update_alt Datasheet

HIV-1 gp120 Monoclonal Antibody (CPAB0714)

The HIV-1 gp120 Antibody (CPAB0714) is a highly specific and sensitive tool for research involving the glycoprotein 120 (gp120) of the Human Immunodeficiency Virus type 1 (HIV-1). This polyclonal antibody, raised in rabbits, exhibits strong reactivity with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.The gp120 protein is a critical component of HIV-1, responsible for binding to the CD4 receptor on the surface of host cells and facilitating viral entry. Understanding the interactions involving gp120 is essential for developing strategies to combat HIV-1 infection and AIDS. The CPAB0714 antibody enables researchers to detect and analyze the expression and localization of gp120 in different cell types, making it an invaluable tool for studies in virology and immunology.

Research into HIV-1 and potential therapeutic interventions relies heavily on accurate and reliable detection of viral proteins such as gp120. The CPAB0714 antibody offers a precise and specific means of studying the role of gp120 in HIV-1 pathogenesis, viral replication, and immune evasion strategies. Its versatility and sensitivity make it an essential reagent for scientists investigating HIV-1 biology and developing novel approaches to combat this global health threat.

Product Name:HIV-1 gp120 Antibody
Product Sku:CPAB0714
Size:2μg
Host Species:
Immunogen:Recombinant HIV-1 gp12 produced in baculovirus expression system.
Clone:
Reactivity:Viral
Applications:Western Blot, ELISA
Purification Method:
Isotype:
Background:Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses.
Synonyms:HIV-1 gp120, HIV1gp120, HIV-I gp120, HIVIgp120.
Storage Buffer:

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