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HistoneH3 Monoclonal Antibody (MACO0671)

SKU:
MACO0671
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Rat
Rabbit
Mouse
Applications:
ELISA
WB
IHC
IP
Conjugation:
Unconjugated
Isotype:
IgG2b
Host Species:
Mouse
€249
Frequently bought together:

Description

HistoneH3 Monoclonal Antibody (MACO0671)

The Histone H3 Monoclonal Antibody (MACO0671) is a vital tool for researchers investigating histones and chromatin regulation. This antibody, produced using a monoclonal approach, is highly specific and exhibits strong reactivity with human samples. It has been validated for use in various applications, including Western blotting and chromatin immunoprecipitation (ChIP).Histone H3 is a key component of chromatin, playing a crucial role in gene regulation and DNA packaging. Aberrant modifications to histone H3 have been linked to various diseases, including cancer. This antibody specifically targets histone H3, enabling the detection and analysis of histone modifications in different cell types and experimental conditions.

It is an essential tool for studies in epigenetics, cancer research, and developmental biology.Understanding the role of histone H3 and its modifications is essential for unraveling the complexities of gene regulation and disease pathogenesis. The Histone H3 Monoclonal Antibody provides researchers with a reliable and specific tool to investigate these processes and advance our understanding of chromatin biology.

Product Name:HistoneH3 Monoclonal Antibody
Product Code:MACO0671
Size: 50µL
Target Names:HistoneH3
Species Reactivity:Human, Rat, Rabbit, Mouse
Host Species:Mouse
Antigen Species:N/A
Tested Applications:ELISA, WB, IHC, IP;
Isotype:IgG2b
Clone ID:1G2E4
Conjugate:Non-conjugated
Clonality:Monoclonal
Antigen:KDIQLARRIRGERA synthetic peptide conjugate to KLH
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:Protein A purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:"Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, H3C1, H3FA, HIST1H3A AND, H3C2, H3FL, HIST1H3B AND, H3C3, H3FC HIST1H3C AND, H3C4, H3FB, HIST1H3D AND, H3C6, H3FD, HIST1H3E AND, H3C7, H3FI, HIST1H3F AND, H3C8, H3FH, HIST1H3G AND, H3C10, H3FK, HIST1H3H AND, H3C11, H3FF, HIST1H3I AND, H3C12, H3FJ, HIST1H3J"
Uniprot ID:N/A
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Others

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