Histone H3.3 Rabbit Monoclonal Antibody (CAB4835)
- SKU:
- CAB4835
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- H3.3A
- H3F3
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Histone H3.3 Rabbit Monoclonal Antibody |
SKU: | CAB4835 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 57-136 of human Histone H3.3 (P84243). |
Sequence: | KSTE LLIR KLPF QRLV REIA QDFK TDLR FQSA AIGA LQEA SEAY LVGL FEDT NLCA IHAK RVTI MPKD IQLA RRIR GERA |
Tested Applications: | WB IHC-P ChIP ChIP-seq ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 ChIP,2μg antibody for 5μg-10μg of ChromatinChIP-seq,1:50 - 1:200 |
Synonyms: | H3F3; H3-3B; H3.3A; H3F3A; BRYLIB1; Histone H3.3 |
Positive Sample: | HeLa,294T,Mouse lungRat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 15kDa |
Observed MW: | 17kDa |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.
Purification Method: | Affinity purification |
Gene ID: | 3020 |
Clone Number: | ARC0255 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |