The HIST1H2BJ Polyclonal Antibody (PACO34630) is a key tool for researchers studying histone H2B, a protein involved in chromatin structure and gene regulation. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in a variety of applications, including Western blotting and immunohistochemistry.Histone H2B is a critical component of nucleosomes, the basic unit of chromatin, and plays a role in DNA packaging and transcriptional regulation. Aberrant expression or modification of histone H2B has been linked to various diseases, including cancer and developmental disorders.
The HIST1H2BJ Polyclonal Antibody allows for precise detection and analysis of histone H2B levels in different cell types, making it essential for studies in epigenetics, cancer biology, and developmental biology.By providing researchers with a reliable tool for investigating histone H2B, the HIST1H2BJ Polyclonal Antibody facilitates a deeper understanding of chromatin dynamics and gene regulation, with important implications for therapeutic developments in various disease contexts.
Antibody Name:
Histone H2B Antibody (PACO34630)
Antibody SKU:
PACO34630
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Cairina moschata
Immunogen:
Recombinant Crocodylus niloticus Histone H2B protein (2-93AA)
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms:
Histone H2B
UniProt Protein Function:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
