Histone H2AX Rabbit Polyclonal Antibody (CAB2082)
- SKU:
- CAB2082
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | Histone H2AX Rabbit Polyclonal Antibody |
SKU: | CAB2082 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human Histone H2AX (NP_002096.1). |
Sequence: | MSGR GKTG GKAR AKAK SRSS RAGL QFPV GRVH RLLR KGHY AERV GAGA PVYL AAVL EYLT AEIL ELAG NAAR DNKK TRII PRHL QLAI RNDE ELNK LLGG VTIA QGGV LPNI QAVL LPKK TSAT VGPK APSG GK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | H2A.X; H2A/X; H2AFX; Histone H2AX |
Positive Sample: | 293T,MCF7,HL-60,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 15kDa |
Observed MW: | 15kDa |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Purification Method: | Affinity purification |
Gene ID: | 3014 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |