Histone H2A.Z Rabbit Monoclonal Antibody (CAB4599)
- SKU:
- CAB4599
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- H2A.Z-1
- H2A.z
- H2A/z
- H2AZ
- Research Area:
- Cell Biology
Description
Product Name: | Histone H2A.Z Rabbit Monoclonal Antibody |
SKU: | CAB4599 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Histone H2A.Z (P0C0S5). |
Sequence: | MAGG KAGK DSGK AKTK AVSR SQRA GLQF PVGR IHRH LKSR TTSH GRVG ATAA VYSA AILE YLTA EVLE LAGN ASKD LKVK RITP RHLQ LAIR GDEE LDSL |
Tested Applications: | WB ChIP ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 ChIP,5μg antibody for 5μg-10μg of Chromatin |
Synonyms: | H2AZ; H2A.z; H2A/z; H2AFZ; H2A.Z-1; .Z |
Positive Sample: | HeLa,293T,U-87MG,Mouse lung,Mouse testis,Mouse brain,Rat lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 13kDa |
Observed MW: | 15kDa |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Purification Method: | Affinity purification |
Gene ID: | 3015 |
Clone Number: | ARC1048 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |