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HIST1H2BC (Ab-5) Antibody (PACO65127)

SKU:
PACO65127
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
IHC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
$383
Frequently bought together:

Description

HIST1H2BC (Ab-5) Antibody (PACO65127)

The HIST1H2BC Antibody (PAC065127) is a high-quality polyclonal antibody designed for research involving the HIST1H2BC protein, which is part of the histone family involved in packaging DNA into chromatin. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blot and immunohistochemistry.HIST1H2BC, a core histone protein, plays a crucial role in gene regulation and chromatin structure, making it a key player in epigenetic processes. Dysregulation of histone proteins like HIST1H2BC has been implicated in diseases such as cancer, where aberrant gene expression contributes to tumorigenesis.

Understanding the function and expression of HIST1H2BC is essential for unraveling the molecular mechanisms underlying disease development and progression.With its high reactivity and specificity to human samples, the HIST1H2BC Antibody (PAC065127) is a valuable tool for researchers studying epigenetics, chromatin biology, and cancer biology. Its ability to detect HIST1H2BC protein in various cell types and tissues makes it versatile for a wide range of research applications, providing crucial insights into the role of histone proteins in health and disease.

Product Name:HIST1H2BC (Ab-5) Antibody
Product Code:PACO65127
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (2-13aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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