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HIST1H2BC (Ab-23) Antibody (PACO65047)

SKU:
PACO65047
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
IHC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319

Description

HIST1H2BC (Ab-23) Antibody (PACO65047)

The Hist1H2bc-AB-23 Antibody (PAC065047) is a polyclonal antibody designed for research involving the Hist1H2bc protein, an integral component of chromatin structure and gene regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.Hist1H2bc is a member of the histone H2b family, playing a critical role in packaging DNA into chromatin and regulating gene expression. Studies have shown that abnormalities in histone proteins can lead to disruptions in chromatin structure, gene expression, and cell function, which may contribute to various diseases, including cancer and developmental disorders.

The Hist1H2bc-AB-23 Antibody enables researchers to detect and analyze Hist1H2bc expression in different cell types, providing valuable insights into the role of this protein in chromatin remodeling and gene regulation. This antibody is an essential tool for studies in molecular biology, epigenetics, and cancer research, offering potential implications for the development of therapeutic strategies targeting histone proteins.

Product Name:HIST1H2BC (Ab-23) Antibody
Product Code:PACO65047
Size:50µL
Target Names:HIST1H2BC
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (17-28aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, H2BFL, H2BFH, H2BFG, H2BFA, H2BFK
Uniprot ID:P62807
Background:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area:Epigenetics and Nuclear Signaling

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